Esophageal squamous-cell carcinoma (ESCC) ranks the fourth leading cause of cancer death and approximate half of the world's 500,000 new ESCC cases each year occur in China. Genomic database of variants for ESCC is a comprehensive database for searching the susceptibility loci (single nucleotide polymorphism, SNP), somatic mutation (single nucleotide variant/indel, SNV/indel) and genes involved in risks for the development of ESCC or survival in patients with the disease. This database integrates the results of genome-wide association study (GWAS) of 2,022 ESCC cases and 2,039 controls, survival GWAS of 1,006 ESCC patients, expression quantitative trait loci (eQTL) of 94 ESCC patients, SNVs/indels in the protein-coding regions from 675 whole-genome sequencing or whole-exome sequencing and their associations with ESCC patients' survival.
Examples: rs1154435, ACAD10, chr6:111,000,000-112,000,000