in 2,022 ESCC cases and 2,039 controls
| SNP | Location | Region | Allele | MAF | P-value | OR(95% CI) | Functional class | Mapped gene(s) | Study |
|---|---|---|---|---|---|---|---|---|---|
| rs1154435 | 4:100285148 | 4q23 | G/A | 0.09 | 1.18E-06 | 1.43 (1.24-1.65) | intergenic | ADH1C(dist=10946), ADH7(dist=48270) | Wu C, et al. (PMID: 21642993), 2011 |
MAF: minor allele frequency in controls
in ESCC tumor or normal tissues of 94 ESCC patients
| SNP | Location | Region | Allele | Effect size | P-value | FDR | Mapped gene(s) | Tissue | Action | Study |
|---|---|---|---|---|---|---|---|---|---|---|
| rs1154435 | 4:100285148 | 4q23 | G/A | -0.73 | 1.49E-04 | 2.69E-02 | ADH1A | Adjacent normal tissue | eQTL boxplot | Chang J, et al. (PMID: 28548104), 2017 |
